Gambaran Jumlah Sel Monosit dan Sel Limfosit Pada Penderita Tuberkulosis Paru di UPTD Rumah Sakit Khusus Paru Provinsi Sumatera Utara
Keywords:
Tuberkulosis Paru, Mycobacterium Tuberkulosis, Monosit dan LimfositAbstract
Pulmonary TB is a chronic infection when associated with M.TB germs. Most mycobacterium tuberculosis germs infect the lungs, this triggers the cause of pulmonary tuberculosis, but these bacteria can infect other parts of the body. Transmission of tuberculosis can be caused by AFB Positive sufferers, AFB Negative sufferers and infections by inhaling air containing sputum microscopically. Tuberculosis is the main cause of monocytosis and lymphopenia. Monocytes are the body's immune response to detect tuberculosis in the form of cellular reactions and formation of the immune response is greatly influenced by the beginning. the body to tuberculosis in cellular reactions and as the main cells forming tubercles, monocytosis is an increase in the number above 900 / mm³. A decrease in the number of lymphocytes indicates an active tuberculosis process; Lymphocytes play an important role in the adaptive immune system against mycobacterium tuberculosis. A decrease in the number of lymphocytes is called lymphopenia below 2000/µL. The purpose of this study was to determine how many monocytes and lymphocytes were found in individuals suffering from pulmonary tuberculosis. Primary and secondary data were used to describe the study design. The laboratory examination method that uses this methodology is automatic, namely the Cell-dyn Emerald 22 hematology analyzer. From the results of the study at the UPTD Special Lung Hospital of North Sumatra Province, 20 samples examined contained 11 samples in a state of monocytosis (55%), 3 samples experienced monocytopenia (15%), and 6 samples with normal monocytes (30%). In lymphocytes there were 2 samples in a state of lymphocytosis (10%), 13 samples in a state of lymphopenia (65%) and 5 samples of normal lymphocytes (25%). An increase in monocytes indicates the activity of tubercle formation in the blood as a sign of active spread of tuberculosis and a decrease in lymphocytes indicates an increased risk of bacterial growth, and the body's ability to fight infection is hampered, resulting in permanent damage and causing lung complications.
Downloads
References
Dotulong, J., Sapulete, M. R., & Kandou, G. D. (2015). Hubungan faktor risiko umur, jenis kelamin dan kepadatan hunian dengan kejadian penyakit TUBERKULOSIS Paru di Desa Wori Kecamatan Wori. Jurnal Kedokteran Komunitas dan Tropik, 3(2).
Kementerian Kesehatan RI. (2018). Pusat data dan Informasi Kementerian Kesehatan RI :Tuberkulosis. Jakarta: Kementerian Kesehatan RI Pusat data dan Informasi ISNN 2442-7659
Azizah, S. (2018). Hitung Jumlah Limfosit dan Monosit Pada Pasien Tuberkulosis Paru Yang Sedang Melakukan Pengobatan di Puskesmas Poasia Anduonohu Kota Kendari. Karya Tulis Ilmiah.
Oehadian,A. 2003.Aspek Hematologi Tuberkulosis. Bandung: FK UNPAD
Kiswari, R. (2014). Buku Ajar Sistem Hematologi dan Transfusi.
Suciyani, S., Naim, N., & Armah, Z. (2018). Analisis Kuantitas dan Hitung Jenis Leukosit pada Petugas Radiologi di Balai Besar Kesehatan Paru Masyarakat (BBKPM) Makassar. Media Kesehatan Politeknik Kesehatan Makassar, 12(1), 59-65.
Ibrahim, R., Setianegara, B., & Hermansyah, H. (2014). Perbandingan nilai darah rutin dan berat badan anak pada pre dan post 2 bulan terapi OAT di Rumah Sakit Khusus Paru-Paru Palembang tahun 2013. JPP (Jurnal Kesehatan Poltekkes Palembang), 1(14), 1-10.
Isbaniah F, et al,2021. Pedoman Diagnosis dan Penatalaksanaan di Indonesia. Jakarta : Perhimpunan Dokter Paru Indonesia
Jones, B. E., Oo, M. M., Taikwel, E. K., Qian, D., Kumar, A., Maslow, E. R., & Barnes, P. F. (1997). CD4 cell counts in human immunodeficiency virus—negative patients with tuberculosis. Clinical Infectious Diseases, 24(5), 988-991.
Rahmaniati, R., & Apriyani, N. (2018). Sosialisasi Pencegahan Penyakit Tuberkulosisc Untuk Masyarakat Flamboyant Bawah Di Kota Palangka Raya: Socialization of TUBERKULOSIS Prevention for Community Flamboyant in Palangka Raya. PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat, 3(1), 47-54.
Oehadian,A. 2003.Aspek Hematologi Tuberkulosis. Bandung: FK UNPAD
Husein, S. G., & Mentari, R. J. (2018). Karakterisasi bakteri Mycobacterium tuberkulosis menggunakan spektrofotometri fourier transform infrared. Jurnal Sains dan Teknologi Farmasi Indonesia, 6(2).
Mardiono, S., Saputra, A. U., & Romadhon, M. (2023). Faktor-Faktor Yang Berhubungan Dengan Peran Keluarga Dalam Pengawasan Menelan Obat Pada Pasien Tuberkulosis Paru. Jurnal Kesehatan Terapan, 10(1), 7-28.
